Lysozyme History
Lysozyme, a remarkable natural antimicrobial and antiviral enzyme, discovered by Alexander Fleming in 1921, when a droplet from Fleming’s nose (who was nursing a cold while working in his lab) accidentally fell into one of the Petri dishes containing microorganisms, noticing the bacteria reaction, Fleming set out to isolate it and find a dissolving bacterial protein, he named it lysozyme.
Lysozyme Introduction
The lysozyme is a kind of Glycoside hydrolases which is widely present in the plant and animal. It mainly acts on the ß-1,4 glycosidic bond between NAM and NAC. The lytic mechanism for bacterial killing by lysozyme include enzymic peptidoglycan hydrolysis of bacterial wall and induction of autolysis that can cause bacterial autolysis.
As a nonspecific immune factors in body fluids and organizaiton, lysozyme participates in kinds of immune response to improve and enhance the swallowing & digestive function of macrophages, and activate sallowing function of other interleukin, then enhance immunity. It can play an important rule in maintaining the intestinal flora balance, promoting the Bifidobacterium proliferation, prevention of enteritis and allergy.In addition, lysozyme also can can directly act on the viral protein with loads, to make the virus inactivation.
Lysozyme Classification
Lysozyme could be divided into different types according to the source: Egg-white lysozyme, Human and mammalian lysozyme, plant derived lysozyme and microbial lysozyme.
At present, the most common is the egg white lysozyme, which is widely used in food and feed industry. But there is an obvious defect - it did not showed satisfactory on gram-negative bacteria.
Microbial Lysozyme
After 16 years R & D, Zhejiang Aegis Biotech Co., Ltd successfully developed and put into production microbial lysozyme, a kind of microbial source one which is fermentated through microbe , using of genetic engineering & technology. It has the function of broad-spectrum antibacterial (both on gram-positive and gram-negative bacteria), anti-inflammatory, anti-virus, enhancing the immunity and repairing injured body tissue, promoting the proliferation of useful bacteria and so on.
Contact
Zhejiang Aegis Biotech Co., Ltd
Add: No.1075, Danfeng Road, Binjiang District of Hangzhou. 310051,China
Tel: +86 571-87692606 Fax: +86 571-85334696
Email: crystal@aegisgroup.cn Skype: crystal001122
Mob/WhatsApp/Viber/Wechat: +86 18920540763
Website: http://www.aegisgroup.cn
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